Last updated on Jun 26, Treatment: 40 mg orally once a day -Duration of therapy: 8 weeks Maintenance: 40 mg orally once daily Comments : -If patients are not healed after 8 weeks or erosive esophagitis EE recurs with the oral formulation, treatment for another 8 weeks may be considered. Oral: 40 mg orally once a day -Duration of therapy: 8 weeks Parenteral: 40 mg via IV infusion once a day, given over at least 2 minutes OR over 15 minutes -Duration of therapy: 7 to 10 days Comments : -IV treatment should be discontinued once the patient is able to take an oral formulation.
Uses : -Short-term treatment of gastroesophageal reflux disease GERD in patients with a history of erosive esophagitis -Reduction of relapse rates of daytime and nighttime heartburn symptoms in adult patients with GERD. Uses : -Treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome -Pathological hypersecretion conditions, including Zollinger-Ellison syndrome.
No adjustment recommended. Pediatric patients: Oral dose reductions should be considered. The IV formulation is not recommended for use in children. This drug may be mixed with apple juice and administered via nasogastric tube. Storage requirements: The manufacturer product information should be consulted. IV compatibility: The manufacturer product information should be consulted.
General : -This drug may be used concomitantly with antacids without affecting the absorption.
Hypochlorhydria (low stomach acid): Causes, symptoms, and treatment
Symptomatic relief may occur after 1 day of treatment, but patients should continue treatment for the full duration to achieve complete symptom control. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Other brands: Protonix , Protonix IV. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
We comply with the HONcode standard for trustworthy health information - verify here. People over the age of 65 have the highest risk. While everyday stress may not have much effect on the production of stomach acid, chronic stress can contribute to hypochlorhydria. Long-term use of antacids or other medications for acid reflux or heartburn may decrease the body's production of stomach acid. Doctors often prescribe medications called proton pump inhibitors to treat acid reflux, and these can cause hypochlorhydria. Over 50 percent of people worldwide are infected with a bacteria called Helicobacter pylori H.
This infection can contribute to low levels of stomach acid and gastric ulcers. Zinc is necessary for the production of stomach acid. A lack of this mineral can contribute to hypochlorhydria. Some surgical procedures, including gastric bypass surgery, can reduce the amount of acid the stomach produces. To diagnose hypochlorhydria, a doctor will typically take a person's medical history and perform a physical exam.
They can also test the acidity of the stomach with a small capsule that contains a transmitter. The person swallows the capsule, and the transmitter reports the amount of acid in the gastrointestinal tract. Doctors measure acidity using the pH scale. A pH value of 3—5 suggests hypochlorhydria, while a pH level of less than 3 indicates normal levels of stomach acid. If the pH value is greater than 5, this suggests an almost complete absence of stomach acid, which is termed achlorhydria.
If the results show hypochlorhydria or achlorhydria, the doctor may take blood tests to check for a deficiency in iron or other nutrients.
A doctor may prescribe HCL supplements to confirm a diagnosis. If a person feels better when taking the supplements, low stomach acid is likely the cause of symptoms. A doctor will usually prescribe at least two antibiotics to take at the same time. Taking a combination of antibiotics prevents the bacteria from developing a resistance to one of the drugs.
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The doctor may need to check whether the H. If they are, the doctor may prescribe a different combination of medications. Long-term use of antacids and proton pump inhibitors can result in hypochlorhydria. A doctor may recommend stopping the use of the drugs or switching to a different treatment. A person may benefit from taking an HCL supplement and a pepsin enzyme to increase stomach acidity. This treatment option may be especially beneficial for older adults experiencing a natural decline in levels of stomach acid.
Natural digestive enzymes are also available in health stores and drugstores. These often contain extracts of papaya and pineapple, which can stimulate the production of stomach acid. A variety of digestive enzyme supplements are also available to purchase online. Reducing chronic stress can restore digestive function. The following lifestyle changes can help:. Avoid foods that are difficult to digest, such as those that are fatty and fried.
Also, chew each bite thoroughly to break the food down and allow it to mix with the digestive enzymes in the mouth. Smaller food particles are more easily digested in the stomach. It is a good idea to avoid eating for at least 3 hours before bedtime. This allows the body to fully digest before sleeping, and it can reduce the risk of nighttime heartburn. For the stomach to produce HCL, the body needs to absorb zinc from the diet.
Zinc-rich foods include:. A low level of stomach acid can result in other deficiencies, such as a lack of iron, vitamin B, and calcium. A doctor or a dietician can help.
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They may recommend taking supplements or increasing dietary intake of these nutrients, especially once a person regains a regular level of stomach acid. If left untreated, hypochlorhydria can negatively impact a person's health and well-being. It is important for people to report associated symptoms and undergo testing. Once a doctor determines why a person's level of stomach acid is low, they can recommend ways to relieve or prevent symptoms.
Prompt treatment also reduces the risk of complications. Treatment options include making dietary and lifestyle changes, taking supplements, and altering the course of medications.
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Britton, E. Ageing and the gut. Proceedings of the Nutrition Society , 72 1 , — Franceschi, F. Role of Helicobacter pylori infection on nutrition and metabolism. World Journal of Gastroenterology , 20 36 , 12,—12, Kines, K. Nutritional interventions for gastroesophageal reflux, irritable bowel syndrome, and hypochlorhydria: A case report. Integrative Medicine: A Clinician's Journal , 15 4 , 49— MLA Leonard, Jayne.
MediLexicon, Intl. APA Leonard, J. MNT is the registered trade mark of Healthline Media.