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Download PDF Chemokine Receptors as Drug Targets, Volume 46 (Methods and Principles in Medicinal Chemistry)

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  • The Hypnotist ...and other tales?
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Sergio A. Lira Prof. Rob Leurs. First published: 27 October About this book Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases.

Types of Drug Receptors

Here is the first reference focusing on these novel drug development opportunities. Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.

Reward Yourself

Reviews "This is an excellent introduction to the topic of chemokine receptors as drug targets. Authors from both academia and the pharmaceutical industry provide updates on the progress in the research on chemokines and their receptors leading to a new approach of drug discovery to target many diseases.

From the very beginning, the series focused on topical volumes covering hot concepts and technologies, and the reader will not miss any important topic in the field. The range of topics is as diverse as are the challenges facing modern drug developers, spanning the fields of organic chemistry, pharmacology, toxicology, life science, and analytics, the latter also including bioinformatics, chemoinformatics and proteomics.


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  5. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. If the address matches an existing account you will receive an email with instructions to retrieve your username. Skip to Main Content. Book Series Book series.

    Structural Analysis of Chemokine Receptor–Ligand Interactions

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