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- The Hypnotist ...and other tales?
- Lost in the Woods.
- Structural Analysis of Chemokine Receptor–Ligand Interactions!
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- The drug–target residence time model: a 10-year retrospective.
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Sergio A. Lira Prof. Rob Leurs. First published: 27 October About this book Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases.
Here is the first reference focusing on these novel drug development opportunities. Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.
Reviews "This is an excellent introduction to the topic of chemokine receptors as drug targets. Authors from both academia and the pharmaceutical industry provide updates on the progress in the research on chemokines and their receptors leading to a new approach of drug discovery to target many diseases.
From the very beginning, the series focused on topical volumes covering hot concepts and technologies, and the reader will not miss any important topic in the field. The range of topics is as diverse as are the challenges facing modern drug developers, spanning the fields of organic chemistry, pharmacology, toxicology, life science, and analytics, the latter also including bioinformatics, chemoinformatics and proteomics.
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Structural Analysis of Chemokine Receptor–Ligand Interactions
About this Book. Vacca retired. Email or Customer ID.